General Cell Based Assays
Eurofins Discoverx PathHunter OSMRb/IL31R Bioassay Kit, 2-Plate. (93-1002Y3-00083)
The PathHunter OSMRb/IL31R Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-31) induced dimerization of OSMRb/IL31R receptors. This product uses EFC technology. The cell line included overexpresses OSMRb target protein fused to PK alongside IL31RA target protein fused to EA. Upon ligand-induced dimerization of OSMRb/IL31R, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Revvity Health Sciences Inc HTRF Human & Mouse Total Histone H3 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total Histone H3 Detection Kit, 500 Assay Points
Sigma Aldrich Fine Chemicals Biosciences Superoxide dismutase-polye1MG
Superoxide dismutase from bovine erythrocytes is a copper and zinc superoxide dismutase. Copper and zinc ions are coordinated by active site histidine residues. It has -barrel structure.
Discovery Life Sciences Gentest CynoMonkey Hep
Gentest Cynomolgus Monkey Hepatocytes Cynomolgus Cryopreserved Suspension Female
Montana Molecular Borealis Arrestin AT1R Assay - 10mL
Measure arrestin signaling kinetics in real time with the live cell, fluorescent Borealis arrestin - Angiotensin II Type I receptor (AT1R) assay. Add the unmodified AT1R and Borealis sensor to cells and measure robust signals the next day on an automated plate reader or fluorescence imaging system. This assay is genetically encoded and packaged in BacMam for efficient transduction in most cell types - including uniform and near 100% efficiency in HEK293 cells as well as expression in many primary or iPSC-derived cells. The kit includes the arrestin sensor BacMam, AT1R BacMam, 500mM sodium butyrate in H2O, and a positive control receptor and agonist (AT1R BacMam and 5mM Angiotensin II in H2O). Borealis kits for several other receptors are also available, and larger-sized kits are available on request. Other Montana Molecular tools including the DAG and Calcium sensors can be used alongside this assay.
Cayman Chemical 2 3cyclIc NADP sodIum sa 7.3mg
A substrate for CNP; has been used in coupled enzyme assays to quantify CNP activity; increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria at 5 µM
Discovery Life Sciences Gentest CD 1 Mouse Hep
Gentest CD 1 Mouse Hepatocytes Cryopreserved Male Plateable Inducible
Discovery Life Sciences Gentest TransportoCellsTM
Gentest TransportoCellsTM Rat Organic Anion transporting Polypeptide 1b2 10e7 cells
Eurofins Discoverx AssayComplete Cell Culture Kit-109, (92-3109G)
AssayComplete Cell Culture Kit-109 is an optimized media kit intended for use in culturing and propagating Eurofins DiscoverX cell lines. This kit contains the base medium, relevant serum, and pen/strep required to produce a full cell culture medium for optimal cell culture results. This product is provided as a 3-component kit which will produce approximately 550 mL of finished media. Please refer to cell line specific datasheet to determine the recommended cell culture kit. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Aat Bioquest Amplite™ Colorimetric Aspartate Aminotransferase (AST) Assay Kit
Aspartate aminotransferase (AST), also called serum glutamic oxaloacetic transaminase (GOT), is a member of transferase family.
Abcam Caspase-1 Assay Kit (Colorimetric)
Caspase-1 Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress ADRB2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0182E2CP0L)
The PathHunter ADRB2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRB2 and EA-tagged β-Arrestin-2. Activation of ADRB2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery R-PLEX Human AFP ASY
The R-PLEX Human AFP Assay from Meso Scale Diagnostics is an electrochemiluminescent immunoassay for the quantitative measurement of alpha-fetoprotein (AFP) in human serum plasma and tissue culture supernatant This assay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to provide a highly sensitive and reproducible method for detecting AFP an important biomarker used to help diagnose and monitor hepatocellular carcinoma and other malignancies as well as fetal defects The assay has a wide dynamic range of 1 95-2000 pg/mL and requires only 50 L of sample
Discovery Life Sciences Gentest Sprague DawlRat Hep
Gentest Sprague Dawley Rat Hepatocytes Cryopreserved Female Plateable Inducible